Did you know that there are actually THREE forms of Estrogens?
It's important to know this stuff, too, because YOU need to be your OWN advocate since even most gynecologists don't know or care about hormones or midlife women's issues!
E1 is called EstrONE. (note the ONE in E1)
E2 is called EstraDIol (note the DI in E2)
E3 is called EsTRIol (note the TRI in E3)
E1 (Estrone) is the form of Estrogen that our Fat cells make. It is the PRIMARY estrogen of the body AFTER menopause. It is also most associated with breast cancer. This is why heavy set women are at much higher risk of breast cancer than thin women. Their ESTRONE levels are higher.
E2 is the form of Estrogen that our ovaries produce before menopause. It has NO increased risk of breast cancer. During the menopausal years and up to 10 years (or more) following menopause, Estradiol actually DECREASES our risk of breast cancer. Unfortunately Estradiol (E2) can convert to Estrone (E1) the estrogen we don't want. THIS is the reason we don't recommend using Estradiol by ITSELF for too many long without mixing it with our "Angel Estrogen" E3.
Now lets examine the Angel Estrogen, E3.
E3 is the form of Estrogen our body makes ONLY when we are pregnant. It DECREASES our risk of breast cancer. It does not have any conversion to Estradiol OR Estrone. It is an "END of the Line" - "END of the Chain" Estrogen. This is the reason Anti-Aging / Functional Medical physicians LOVE Estriol (E3).
Heaven is 80% E3 and 20% E2 (as well as mixed with the perfect ratio of Progesterone.) It is a LOVELY and PROVEN combination of Safe and Effective Bioidentical Replacement! It's perfect for a couple years before menopause to "whenever" AFTER menopause if you are thin OR up to 3-5 years after menopause if you need to lose weight.
Protect is Progesterone ONLY good for younger women.
Support is 100% E3 and Progesterone for years after menopause. Good for women who need to lose weight and their E1 levels may already be higher than optimal.
Hope this helps you understand the critical differences of the three Estrogens!